Medicinal products which induce hepatic microsomal enzymes such as alcohol, barbiturates, monoamine oxidase inhibitors and tricyclic antidepressants, may increase the hepatotoxicity of paracetamol particularly after overdose. Monoamine oxidase inhibitors (including moclobemide): hypertensive interactions occur between sympathomimetic amines such as phenylephrine and monoamine oxidase inhibitors (see section 4.

Seek advice before using if you are breast feeding, pregnant, planning to become pregnant, or suffer from allergies. Lemsip Max Cold and Flu Honey and Ginger Sachets provide warming comfort and relief from symptoms of cold and flu. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. Both paracetamol and phenylephrine hydrochloride are recognised and frequently utilised components for addressing cold and flu symptoms.You suffer from severe renal or hepatic impairment, as paracetamol might need to be adjusted or monitored. This means the packaging is plain, there is no mention of what product is inside your package and there is no mention of Chemist4U either. Do not take if: Allergic to any ingredient, if you have heart disease, high blood pressure, overactive thyroid, have had peptic ulcer, or you are taking or have taken MAOI's (antidepressants) within 14 days. Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage. You suspect an overdose, as immediate medical attention is crucial due to the risk of delayed liver damage.

Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol; however, the maximum protective effect is obtained up to 8 hours post-ingestion.Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage.