Pure Encapsulations - Vitamin B-Complex Plus - Balanced B Vitamin Formula with Active Folate - 60 Capsules

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Several B vitamins are used by the body during physical activity for energy production, tissue regeneration, and more. This makes it especially important for athletes and anyone active to meet their vitamin B needs through foods or supplements. Cirillo M, et al. (2021). 5-methyltetrahydrofolate and vitamin B12 supplementation is associated with clinical pregnancy and live birth in women undergoing assisted reproductive technology. Plus, it’s formulated with well-absorbed forms of all eight B vitamins, including 5-MTHF and methylcobalamin, along with Benfopure benfotiamine, a compound similar to thiamine believed to have anti-inflammatory properties. Vitamin B complex supplements are available in several forms, including capsules and liquid. Evidence suggests there’s not a significant difference in the effectiveness of these forms.

As a food supplement, take 1 capsule daily, with a meal, or as directed by your healthcare professional. Precautions Allowitz KV, et al. (2022). Therapeutic potential of vitamin B1 derivative benfotiamine from diabetes to COVID-19. Razak MA, et al. (2017). Multifarious beneficial effect of nonessential amino acid, glycine: A review. people taking certain medications, such as diabetes medications and proton pump inhibitors like Prilosec Kim J, et al. (2019). Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes.Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Folate prevents neural tube defects during pregnancy and may even protect against heart disease, cancer, and cognitive dysfunction.

Nordic Naturals Vitamin B Complex contains all eight B vitamins in absorbable forms, including methylcobalamin, which is the active form of B12, and 5-methyltetrahydrofolate (5-MTHF), which is the biologically active form of folate. Tardy A-L, et al. (2020). Vitamins and minerals for energy, fatigue and cognition: A narrative review of the biochemical and clinical evidence. Sil A, et al. (2018). A randomized, open labeled study comparing the serum levels of cobalamin after three doses of 500 mcg vs. a single dose methylcobalamin of 1500 mcg in patients with peripheral neuropathy.

For the past three years I have been experiencing increasing sciatic nerve pain in the morning and intermittent episodes during the day. At 81-years-old, I’m thinking my mobility is in peril. features folate as 5-methyltetrahydrofolate (5-MTHF), the universally metabolised and biologically active form of folate Mahdavifar B, et al. (2021). Dietary intake of B vitamins and their association with depression, anxiety, and stress symptoms: A cross-sectional, population-based survey.