At Longevity Blog, we help you sort through the hype and get down to the real results you want, by helping you to test before & after results yourself. Our job is to ask targeted questions of the founders and lead scientists at longevity tech companies, to help direct your personal investment into your own longevity strategy, effectively. We’d like to start by better understanding two concepts that your team uses. One is “ topical supplement”.

Rich in phospholipids such as sunflower and lecithin, omega 3 and 6 fatty acids, jojoba esters and macadamia emollients making One Truth 818 Serum incredibly hydrating to the skin. As well as phenomenal visual age reversal of the skin, tests also show a decrease in transepidermal water loss from use of One Truth 818 Serum. Upon further research and consultation, I found none of these things are actually true. But what is important to note is that there are a variety of factors that go into a successful treatment regimine that will actually have a meaningful impact on your aesthetic age. Let's extend that a little bit to where you think this technology is going. Specifically, where OneSkin as company is going over the next 5 years? OneSkin is a Longevity Technology Company Telomere dysfunction is now known to be one of the causes of aging. Within the skin, increasing amounts of evidence are linking telomere ‘attrition’ (shortening) to skin aging, but more research is needed to demonstrate the direct link between telomerase and improved skin health.LB: This leads directly into our next question – on the topic of human skin equivalents you have samples of cells from young through to aged skin – but you also work on actually “aging” human skin in the lab, namely with UV radiation. RD: When you are exposed to UV radiation, you damage parts of your DNA. This includes the telomeres, which are the tips of your DNA, there to protect your DNA.

We assessed all the parameters after 6 weeks and 12 weeks. One of the most interesting results that we got from this study was an improvement in the skin barrier, which happened only on the side of the face that was treated with the OS-01 peptide. As Dr Reis pointed out, this is one of the primary drivers of skin aging, and in fact, OneSkin uses UV radiation in the lab to artificially age their 3D human skin equivalents. We know many products cause irritation and inflammation to the skin which leads to forced repair through cell division, accelerated telomere shortening and ultimately, premature ageing. The New One Truth 818 Anti-Ageing Cleanser follows the scientific principles of Corneotherapy: to repair and maintain the skins barrier and integrity while effectively cleansing it.A Visia scan also will provide you with the “ TruSkin Age” of your face, which we have deemed your ‘ Aesthetic Age’ (analogous to your biological age), revealing how old you look, based on a pretty comprehensive algorithm. I envision a future in which we'll be able to control or fine-tune aging at the molecular level. We'll be able to actually regulate the aging process. LB: That's really a sign of tenacity, as you've just shared and Bill Andrews is clearly a very important figure in the history behind the science and has a relationship with your company.